ACC · harvested 2026-11-07
Adrenocortical carcinoma: open trials
Every trial listing this cancer, plus rare-tumour and solid-tumour studies that accept it, from the three registries. The grade is a text analysis of published inclusion and exclusion criteria against what you enter; the trial team confirms eligibility. A trial being open is not the same as it being reachable, so read Routes in too.
35 open trials.
2022-500013-32-01 · NCT03583710 · Phase 3
Adjuvant therapy in high risk adrenocortical carcinoma (ADIUVO-2)Uppsala University Hospital
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: France, Germany, Netherlands, Poland, Sweden, United States
Enter details to grade2025-522757-19-00 · ISRCTN15479264 · Phase 2
A phase II trial of CY-101 in participants with adrenocortical cancer.Cancer Research UK
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: France, Germany, Norway, Spain, United Kingdom
Enter details to gradeNCT00453674 · observational
German Adrenocortical Carcinoma RegistryUniversity of Wuerzburg
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: Germany
Enter details to gradeNCT03050268 · observational
SJFAMILY: Familial Investigations of Childhood Cancer PredispositionSt. Jude Children's Research Hospital
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT04897321 · PHASE1
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)St. Jude Children's Research Hospital
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT05237934 · observational
Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)National Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT05286814 · PHASE2
PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaNational Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06041516 · PHASE1
A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath TumorsNational Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06487481 · PHASE1
Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical CarcinomaNational Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06900595 · PHASE2
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical CancerNational Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT07189403 · 2025-521886-28-00 · PHASE1
A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate CancerDaiichi Sankyo
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- EU CTIS reports this trial halted — check with the site before you apply
- Sites: France, United Kingdom, United States
Enter details to gradeNCT07920198 · observational
ADRENALINK: Adrenal Diseases in the Population of Modena: A Clinical-Epidemiological Database of Patients Referred to the Adrenal Disorders Outpatient Clinic of the Clinical Unit of Endocrinology at the Modena University Hospital (AOU Modena)Azienda Ospedaliero-Universitaria di Modena
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: Italy
Enter details to gradeNCT00669266 · observational
Adrenal Tumors - Pathogenesis and TherapyUniversity of Wuerzburg
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: Germany
Enter details to gradeNCT04119024 · PHASE1
Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid TumorsAnusha Kalbasi
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06006013 · PHASE2
Cabozantinib in Combination With Pembrolizumab for the Treatment of Patients With Locally Advanced, Metastatic, or Unresectable Adrenal Cortical CancerEmory University
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06066333 · PHASE2
Study of Radiotherapy and Pembrolizumab in People With Adrenocortical CarcinomaMemorial Sloan Kettering Cancer Center
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: United States
Enter details to gradeNCT06141369 · NA
Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)Shanghai Jiao Tong University School of Medicine
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: China
Enter details to gradeNCT06333314 · PHASE2
Pan-MSI-ACSE: Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSIUNICANCER
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: France
Enter details to gradeNCT07335679 · observational
CCSTR: Characterization of the Strasbourg Cohort of Patients With Adrenal Cortex CarcinomaUniversity Hospital, Strasbourg, France
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: France
Enter details to gradeNCT05913427 · PHASE2
PESETA: Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC)Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: Italy
Enter details to gradeNCT06587802 · PHASE2
Phase II Study of PD-1 Antibody Combined With Radiotherapy in Recurrent or Metastatic Adrenal Cortical CarcinomaSun Yat-sen University
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: China
Enter details to gradeNCT06683846 · PHASE2
Ivonescimab in the Treatment of Multiple Advanced TumorsFudan University
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: China
Enter details to gradeNCT06831175 · PHASE2
Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical CarcinomaWest China Hospital
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: China
Enter details to gradeNCT07085572 · 2024-520449-21-00 · PHASE2
INTERVAL: Cemiplimab as Maintenance Treatment for Advanced Adrenocortical CancerAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
- Lists adrenocortical carcinoma as a condition
- Recruiting now
- Sites: Italy
Enter details to grade2024-520160-34-00 · Phase 2
PROSPECTIVE, PHASE II STUDY TO EVALUATE THE EFFICACY OF ADDITION OF PROGESTERONE TO STANDARD CHEMOTHERAPY ACCORDING TO EDP SCHEME PLUS MITOTANE IN PATIENTS WITH ADVANCED ADRENAL CORTICAL CARCINOMA - PESETA TRIALAzienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
- Lists adrenocortical carcinoma as a condition
- Approved to run; CTIS does not say whether it is recruiting — ask the site
- Sites: Italy
Enter details to grade2026-525406-36-00 · Phase 2
Hyperthermic Intraperitoneal Chemotherapy and Regional Adrenalectomy in the management of Stage II & III Adrenocortical Carcinoma.Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
- Lists adrenocortical carcinoma as a condition
- Approved to run; CTIS does not say whether it is recruiting — ask the site
- Sites: Italy
Enter details to gradeNCT07715903 · PHASE1
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump TherapyNational Cancer Institute (NCI)
- Lists adrenocortical carcinoma as a condition
- Not yet recruiting
- Sites: United States
Enter details to gradeNCT07743138 · PHASE2
STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL)M.D. Anderson Cancer Center
- Lists adrenocortical carcinoma as a condition
- Not yet recruiting
- Sites: United States
Enter details to grade2024-512019-36-00 · Phase 1
A first-in-human clinical study to assess safety and tolerability of genetically modified T-cells in ROR1 positive tumorsUniversitaetsklinikum Wuerzburg AöR
- Lists adrenocortical carcinoma as a condition
- Approved to run; CTIS does not say whether it is recruiting — ask the site
- Sites: Germany
Not yet checkedNCT03474237 · observational
A Prospective Cohort Study for Patients With Adrenal DiseasesSeoul National University Hospital
- Lists adrenocortical carcinoma as a condition
- Enrolling by invitation only
- Sites: South Korea
Enter details to gradeNCT07141147 · NA
A Prospective, Randomized, Multicenter Clinical Study Comparing Adjuvant Radiotherapy Versus Observation in High-risk Localized Adrenocortical Carcinoma After Surgery.Sun Yat-sen University
- Lists adrenocortical carcinoma as a condition
- Not yet recruiting
- Sites: China
Enter details to gradeNCT03739827 · observational
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid TumorsNational Cancer Institute (NCI)
- Open to any rare solid tumour, so this cancer qualifies
- Recruiting now
- Sites: United States
Enter details to gradeNCT06607692 · PHASE1, PHASE2
LUPARPED: Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).Fundación de investigación HM
- Open to adrenal tumours, which includes this cancer
- Recruiting now
- Sites: Spain
Enter details to gradeNCT07072143 · observational
PARTNER: An International Study on Pediatric Patients With Rare Tumors.Azienda Ospedaliera di Padova
- Open to any rare solid tumour, so this cancer qualifies
- Recruiting now
- Sites: Italy
Enter details to grade2023-506888-34-00 · Phase 1
A Phase 1a/1b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of the CDK4 Inhibitor BGB-43395, Alone or as Part of Combination Therapies in Patients With Metastatic HR+/HER2- Breast Cancer and Other Advanced Solid TumorsBeOne Medicines AG
- Open to advanced solid tumours of any type; ask whether this cancer is accepted
- Approved to run; CTIS does not say whether it is recruiting — ask the site
- Sites: France
Not yet checked
Not recruiting new patients
Listed so you know they were checked. Some are still running and could reopen; the status beside each one is the registry's.
- terminated
- ISRCTN13877559Gut bacteria and their association with chemotherapy response in early breast cancer patientscompleted
- terminated
- ISRCTN17127122Efficacy of intra-articular collagen injection in patients with knee joint pain compared to normal saline injectioncompleted
- ISRCTN20220821Rescue of ADdiSon’s disease 2completed
- ISRCTN41325341Prednisolone in adrenal insufficiency diseasecompleted
- ISRCTN67193733The Pulses Studycompleted
- completed
- active not recruiting
- NCT00568139Evaluation of Side Effects of Mitotaneactive not recruiting
- active not recruiting
- active not recruiting
- active not recruiting
- active not recruiting
- active not recruiting
- active not recruiting
- active not recruiting
- NCT03833700A Study of E7386 in Participants With Advanced Solid Tumor Including Colorectal Cancer (CRC)active not recruiting
- active not recruiting
- terminated
- active not recruiting
- NCT05563467 · 2024-517205-82-00Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma.active not recruiting